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[78] revealed that 2550 g/mL Am-EVs in an LPS-induced Caco-2 inflammation model precisely modulated the MAPK signaling cascade through coordinated downregulation of TRIF/MyD88/p38 MAPK/FOS and upregulation of TGFBR2, leading to marked reductions in oxidative stress markers (ROS, MDA), restored catalase activity, and suppressed pro-inflammatory cytokine (TNF-/IL-1/IL-6) expression
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Schwarz, Line Rasmussen, Malte E
Managing pasireotide-associated hyperglycemia: a randomized, open-label, phase IV study
Wegovy was given as a once-weekly pen injection starting at a low dose that was gradually increased to a maximum of 2.4mg over a period of 68 weeks
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