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Tears of patients with dry eye show significantly increased osmolarity, with a mean value of 343 mOsm compared with 302 mOsm in healthy controls [162]

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This study further suggests the involvement of various candidate genes in HMs tolerance processes and their prospects in developing HMs-tolerant genotypes through breeding programs

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The renin-angiotensin system (RAS) plays an essential role in blood pressure regulation, and Ang II is a well-known pressor peptide associated with RAS