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Lillys move comes amid intensifying competition in the obesity market, particularly against semaglutide-based products

More recently, orally active small-molecule GLP-1R agonists have emerged as an alternative to injectable peptide drugs

It showed similar results: participants who took the drug lost an average of 15 percent of body weight lost, whereas those who took the placebo lost an average of just 2.4 percent

It is important to note that there is no definitive evidence establishing a permanent taste alteration with GLP-1 therapy, and individual experiences vary considerably

Lancet 2026

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