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Always follow the specific instructions provided by your [compounding pharmacy](/oem) and prescribing clinician.* --- ## References - [Mounjaro (tirzepatide) Prescribing Information]( *Eli Lilly and Company*, 2024
Tirzepatide, the active ingredient in Zepbound, works by mimicking two hormones that regulate appetite and blood sugarGLP-1 and GIP
While insulin glargine primarily reduced fasting glucose levels and actually increased body weight, exenatide decreased fed glucose levels and body weight while also reducing risk of nocturnal hypoglycemia [44]
The energy expenditure effects contribute to Retatrutide's superior weight loss efficacy compared to GLP-1-only therapies
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