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It promotes dendritic spine formation and increases synaptic connectivity in preclinical models of neural development
Blocking FOXO4, which inhibits the activation of P53, causes senescent cells to undergo apoptosis by P53 activation, without affecting healthy cells around them, and has anti-aging effects which may have potential applications in the treatment of numerous age-related diseases, as well as an adjunct to treatment for certain forms of cancer
All housing, handling, and experimentation that involved the rats were conducted following the procedures set in place by the National Institutes of Health guide for the care and usage of laboratory animals [2]
Wissenschaftliche Quellen & Referenzen: FDA (U.S
Tandon et al., 2022