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Phase I data and clinical experience report no serious adverse events at doses up to 10 mg per injection

Tendon Fibroblast Outgrowth Chang et al., Journal of Applied Physiology (2011) Chang and colleagues conducted an in vitro study using tendon fibroblasts isolated from the Achilles tendons of male Sprague-Dawley rats

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No adverse events caused treatment discontinuation and the 3 serious adverse events that occurred were not related to the investigational drug