Future work will explore further optimization of drug release kinetics, long-term safety across larger animal models, and eventual clinical translation of this technology for type 2 diabetes and metabolic disorders
Deinlein U, Stephan AB, Horie T et al (2014) Plant salt-tolerance mechanisms
Its goal is systemic saturation, so local injection is unnecessary and wasteful
It also exhibits analgesic and anti-inflammatory properties, accelerating the healing of sprains, tears, and tissue damage by increasing blood flow to injured areas
Banger KK et al
A study measuring only serum KLOW concentration would conclude the compound is "gone" by 48 hours, but tissue samples taken at 7296 hours post-administration still show elevated phosphorylated AMPK levels, indicating ongoing metabolic effects