Disruptions in mitochondrial function lead to increased oxidative stress, cellular damage, and eventual neurodegeneration (Anderson et al., 2023)
Crumbly tablets or effervescent tablets that no longer dissolve properly also indicate that the product should no longer be used
A couple of studies found no benefits of B12 for lowering homocysteine in HD patients, one used oral B12, 2000 g three times per week for 6 weeks, 55 the other used methyl-B12 i.m
Green tea contains catechins that may stimulate GLP-1 secretion in some studies
Physicians respond better to informed patients who understand what they are requesting and why
However, novel dual receptor agonists have been developed for the treatment of obesity and T2D under the concept that GLP-1 restrains the hyperglycemic action of glucagon, while allowing it to exert its beneficial actions on bodyweight, food intake, lipid metabolism and thermogenesis (71)