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Patients taking insulin or sulfonylureas should be particularly vigilant about hypoglycemia risk if nausea reduces food intake, and may need adjustment of these medications

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While an 11.2 percent average weight loss is clinically significant, it trails behind the 13.7 percent average reduction seen with semaglutide and 20.2 percent with tirzepatide

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The business case (and the human case) for preventing GLP-1 bias GLP-1 bias is not a side issue