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CagriSema produced unprecedented mean weight loss of 20.4% at 68 weeks on an intent-to-treat basis, significantly exceeding semaglutide alone (14.9%), cagrilintide alone (11.5%), and placebo (3.0%)

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Studies have demonstrated that Epithalon influences gene expression at the epigenetic level, inducing decondensation of heterochromatin near centromeres in aged lymphocytes and activating previously silenced genes