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In vitro, GLP-1 enhanced brain-derived neurotrophic factor (BDNF) secretion and ameliorated mitochondrial dysfunction and cell toxicity via cAMP/PKA activation in A-treated astrocytes [50]

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6 Semaglutide mimics incretin hormones, enhancing insulin secretion, delaying gastric emptying, and suppressing appetite, leading to approximately 12% weight loss in clinical trials