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It is unknown whether this drug causes thyroid C-cell tumors (including medullary thyroid carcinoma [MTC]) in humans as human relevance of drug-induced rodent thyroid C-cell tumors has not been established
Cardiac Bock-Marquette et al
Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau
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(Keep Dupixent in its original carton.) After removing Dupixent from the refrigerator, you should use the medication within 14 days
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