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The following areas summarize how the peptide has been examined in published academic and laboratory work, framed solely as a literature review of in vitro investigation: Fragment-specific activity: In vitro models have evaluated it as a modified C-terminal hGH fragment that can be examined independently of classical hGH receptor signalling, separating fragment-specific behaviour from the actions of full-length growth hormone
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Due to its effects on glucose metabolism, GLP-1 and its synthetic agonists have become key pharmacological agents in the treatment of type 2 diabetes (T2D) [2]
Protein kinase B activation by reactive oxygen species is independent on tyrosine kinase receptor phosphorylation and required Src activity
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