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Stephen Appezzato Key Takeaways Federal exclusion of weight-loss drugs forces Medicare GLP-1 utilization into other FDA-approved indications, even as 2024 Part D gross GLP-1 spending reached $27.5 billion across 21.8 million claims
Sources Targher G, Valenti L, Byrne CD
Clinicians should carefully consider use in patients with significant motility disorders, inflammatory bowel disease with strictures, or severe chronic constipation
According to the FDA and the American Pharmacists Association , symptoms of Ozempic overdose may include: Severe vomiting Severe hypoglycemia (low blood sugar levels) Abdominal pain Fainting Headache Migraine Dehydration Weakness Loss of appetite Acute pancreatitis Gallstones Some of these gastrointestinal symptoms, such as nausea and vomiting, can last for days , and some cases of Ozempic overdose require hospitalization
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