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Mutation: ADAMTS2 gene
Der Hund ist homozygot für das normale Allel
Digitale Verwaltung über myFERAGEN: Alle Ergebnisse dauerhaft gespeichert
Such heterozygous animals will show clinical signs which will decrease their quality of life
dragging of paws and loss of conscious proprioception
Kehlkopflähmung und Polyneuropathie Typ 3 (LPPN3) Mischling Mutation: ADAMTS2 geneLaryngeal paralysis associated with a generalized polyneuropathy (LPPN) is an inherited disease affecting several dog breeds, including Leonbergers, Saint Bernards and Labrardor retrievers. Laryngeal paralysis results in the loss of function of the laryngeal nerves and muscles controlling the opening of the laryngeal cartilages during breathing and closing during swallowing food. Affected dogs have difficulty breathing accompanied by a high pitched
