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dass es keinen genauen genetischen Risikofaktor gibt und auch andere genetische oder umweltbedingte Faktoren die Entwicklung und das Fortschreiten der Krankheit beeinflussen können
The symptoms usually occur at the age of 3 months and include progressing generalized cerebellar ataxia
Mutation: RSPO2 gene
chronic pain
gland or other kidney diseases
Neuroaxonale Dystrophie (NAD) - Papillon ISAG dass es keinen genauen genetischenNeuroaxonal dystrophy (NAD) is an autosomal recessive genetic disease in Papillon and some other breeds. NAD is characterized by neurodegenerative pathology of the central and peripheral nervous system in which swellings (spheroids) develop and accumulate along axons throughout the brain and spinal cord. Affected Papillons show various neurological deficits including gait abnormalities, ataxia, tremor, lack of coordination and various behavioural
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