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incoordination of voluntary movements (ataxia)
This often leads to chronic kidney failure and shortened life span
Mutation: FUCA1 gene
agouti coat patterns are not expressed due to dominant KB allele
Clinical signs in Leonberger vary greatly and have different age of onset from <1 year to 10 years of age
Leukozyten Adhäsionsdefizienz Typ III (LAD3) Katzen incoordination of voluntary movements (ataxia)Leukocyte adhesion deficiency (LAD3) is a rare canine autosomal recessive disorder characterised by failure of activation of beta 13 type integrins, expressed on haematopoietic cells. That results in bleeding diathesis, while leukocyte count remains normal. The symptoms start to show at around 6 months of age and include abnormal bleeding, dental disease, pyrexia, lameness and infections, such as deep pyoderma, pododermatitis, gingivitis and
US$ 247.50
US$ 132.50
US$ 132.50
