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Other clinical signs include left-right body asymmetry due to disruption of embryonic development and impaired male fertility due to defects of the spermatozoa flagella
Gesunde Welpen beginnen mit einer durchdachten genetischen Entscheidung
Mutation: PLG gene
⚠️ Important note:
Mutation: KCNJ10 gene
Multifokale Retinopathie 3 (CMR3) option-set-443684-checkbox-1 Other clinical signs include left-rightCanine multifocal retinopathies (CMR) are a group of inherited eye diseases. The diseases were reported in mastiff related breeds (CMR1), Coton de Tulear (CMR2) and in Lapponian herder (CMR3). CMR1 is found in different dog breeds, whereas CMR2 and CMR3 are so far exclusive to a single dog breed each. While exhibiting similar clinical symptoms comparable to CMR1 and CMR2, CMR3 is predicted to be based on a distinctly different molecular mechanism.
