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Cone–rod dystrophy 1 (cord1 - PRA) is a retinal disease associated with RPGRIP1 gene first described in Dachshund
die das Axon von Nervenzellen umgibt und eine wichtige Rolle bei der Funktion des Nervensystems spielt
Mutation: TNR gene
Mutation: KCNJ10 gene
Three different alleles are described on K-Locus with following hierarchy: KB (dominant black) > kbr (brindle) > ky (normal)
Thrombopathie - American Eskimo Dog Diversität Cone–rod dystrophy 1 (cord1 -Thrombopathia is an inherited platelet disorder. Affecteddogs have abnormal platelet function because they are not able to stick together properly and therefore cannot form a clot. Dogs exhibit typical signs of platelet defects including bleeding from snouts, gingival bleeding,and petechiation. Other symptoms include weakness and rear limb paralysis secondary tospinal cord hemorrhage. The platelet defect is characterized by impairedor absent platelet
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